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Date |
Event(s) |
| 1 | 1563 | - 1563—1564: London Plague
Bubonic plague epidemic - London, England.
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| 2 | 1592 | - 1592—1596: Seneca Nation measles epidemic
Affected an unknow number of Seneca natives in North America
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| 3 | 1603 | - 1603: London plague epidemic
Bubonic plague epidemic in London, England that killed 40,000 people.
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| 4 | 1605 | - 1 Apr 1605—27 Apr 1605: Pope Leo XI
Alessandro Ottaviano de' Medici, born on 2 June 1535 in Florence, Duchy of Florence
- 16 May 1605—28 Jan 1621: Pope Paul V
Camillo Borghese, born on 17 September 1550 in Rome, Papal States
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| 5 | 1616 | - 1616—1620: New England infections epidemic
Affected Southern New England, British North America, especially the Wampanoag people, and killed an estimated 30% to 90% of specific populations.
Unknown source, possibly leptospirosis with Weil syndrome. Classic explanations include yellow fever, bubonic plague, influenza, smallpox, chickenpox, typhus, and syndemic infection of hepatitis B and hepatitis D
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| 6 | 1621 | - 9 Feb 1621—8 Jul 1623: Pope Gergory XV
Alessandro Ludovisi, born on 9 January 1554 in Bologna, Papal States
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| 7 | 1623 | - 6 Aug 1623—29 Jul 1644: Pope Urban VIII
Maffeo Vincenzo Barberini, born on 5 April 1568 in Florence, Grand Duchy of Tuscany
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| 8 | 1633 | - 1633—1634: Massachusetts smallpox epidemic
Made about 1,000 victims
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| 9 | 1634 | - 1634—1640: Wyandot People epidemic of infections
Killed between 15,000 and 25,000 Wyandot people of North America.
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| 10 | 1637 | - 1637—1637: London plague epidemic
Bubonic plague epidemic in London and Westminster, England - Killed about 10,000 people
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| 11 | 1644 | - 15 Sep 1644—7 Jan 1655: Pope Innocent X
Giovanni Battista Pamphili, born on 6 May 1574 in Rome, Papal States
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| 12 | 1655 | - 7 Apr 1655—22 May 1667: Pope Alexander VII
Fabio Chigi, born on 13 February 1599 in Siena, Grand Duchy of Tuscany
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